DOES NSAID EXACERBATED RESPIRATORY DISEASE (N-ERD) ACCOMPANYING SEVERE ASTHMA AFFECT BIOLOGICAL TREATMENT RESPONSE? EFFICACY OF OMALIZUMAB AND MEPOLIZUMAB IN N-ERD

Introduction: Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) accompanies severe asthma in about 15% of the patients and may adversely affect the prognosis.Omalizumab and mepolizumab are biologics used in patients with severe asthma.The objective of this study is to assess the respiratory improvements, after the

Teenagers are a group of young people in the transition from children Smoothie to adulthood.At this particular period adolescents have experienced rapid physical and psychological development in which physically they are considered to be adults but psychologically immature.In terms of biological development, most teenagers are mature, but socially,

The World Health Organization (WHO) predicted that 10 Autumn / Apple million people would have died of cancer by 2020.According to recent studies, liver cancer is the most prevalent cancer worldwide.Hepatocellular carcinoma (HCC) is the leading cause of early-stage liver cancer.However, HCC occurs most frequently in patients with chronic liver cond

blade blank The Active Peptide from Shark Liver (APSL) was expressed in E.coli BL21 cells.The cDNA encoding APSL protein was obtained from shark regenerated hepatic tissue by RT-PCR, then it was cloned in the pET-28a expression vector.The expressed fusion protein was purified by Ni-IDA affinity chromatography.SDS-PAGE and HPLC analysis showed the p

Cryptosporidiosis is a waterborne disease, has as aggravating the difficulty of preventing environmental contamination and lack of effective therapeutic measures.With marked importance to the cattle, causes inflammation and intestinal villous atrophy resulting in loss of absorptive surface.This study aimed to perform molecular characterization of C